Higuchi Fumi

Researcher Information

Affiliation

Clinical Medicine Senior Assistant Professor
Department of Neurosurgery Senior Assistant Professor

URL

https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201901013832638234

Research funding number

• 20537104

J-Global ID

• 201901013832638234

Research Areas

• Life sciences / Neurosurgery

Academic & Professional Experience

• 2023/10 - Today  Teikyo University
• 2017/10 - 2021/07  Dokkyo Medical UniversityNeurosurgery
• 2015/05 - 2017/09  Massachusetts General HospitalNeurosurgeryresearch fellow
• 2007/04 - 2015/04  Dokkyo Medical UniversityNeurosurgery

Research Activity Information

Published Papers

• Endoscopic Endonasal Transsphenoidal Surgery for Intrasellar Mixed Germ Cell Tumors.

  Yoshiaki Goto; Fumi Higuchi; Mitsuteru Hiwatari; Yuko Sasajima; Masahiro Shin

  World neurosurgery 186 165 - 165 2024/04
• 腫瘍内出血で急性水頭症をきたした中脳被蓋部腫瘍の一例

  中村 祐基; 樋口 芙未; 樋渡 光輝; 大本 裕次郎; 井上 雄貴; 川口 愛; 富岡 亜梨沙; 大山 裕太; 後藤 芳明; 宇野 健志; 庄島 正明; 石田 毅; 笹島 ゆう子; 辛 正廣

  小児の脳神経 (一社)日本小児神経外科学会 49 (2) 229 - 229 0387-8023 2024/04
• 視神経鞘髄膜腫との画像上鑑別が困難であった眼窩内isolated optic nerve lymphomaの1例

  横井 利光; 樋口 芙未; 木倉 亮太; 後藤 芳明; 平田 操; 庄島 正明; 羽賀 敏博; 笹島 ゆう子; 辛 正廣

  CI研究 日本脳神経CI学会 45 (3-4) 109 - 114 0918-7073 2024/03
• Rise of oligodendroglioma hypermutator phenotype from a subclone harboring TP53 mutation after TMZ treatment

  Fumi Higuchi; Takeo Uzuka; Hadzki Matsuda; Takuma Sumi; Kayoko Iwata; Takashi Namatame; Masahiro Shin; Hiroyoshi Akutsu; Keisuke Ueki

  Research Square Platform LLC 2023/09
• 化学療法中に大脳に形質細胞腫を生じた多発性骨髄腫の1例

  金野 巧; 松本 謙介; 樋口 芙未; 宇於崎 宏; 白崎 良輔; 荒井 翔也; 松尾 琢二; 田代 晴子; 上妻 謙

  日本内科学会関東地方会 日本内科学会-関東地方会 687回 35 - 35 2023/06
• Efficacy of a Novel Augmented Reality Navigation System Using 3D Computer Graphic Modeling in Endoscopic Transsphenoidal Surgery for Sellar and Parasellar Tumors.

  Yoshiaki Goto; Ai Kawaguchi; Yuki Inoue; Yuki Nakamura; Yuta Oyama; Arisa Tomioka; Fumi Higuchi; Takeshi Uno; Masaaki Shojima; Taichi Kin; Masahiro Shin

  Cancers 15 (7) 2023/04
• A modified surgical technique for the Jarvik 2000 using a postauricular approach.

  Ikuko Shibasaki; Hironaga Ogawa; Fumi Higuchi; Takashi Kato; Hirotsugu Fukuda

  Surgery today 52 (5) 863 - 865 2022/05
• Gene expression profiling of 19q-loss astrocytomas suggest a specific pattern associated with the better prognosis.

  Ryohei Otani; Akitake Mukasa; Takeo Uzuka; Fumi Higuchi; Hadzki Matsuda; Masashi Nomura; Shota Tanaka; Phyo Kim; Keisuke Ueki

  Journal of neuro-oncology 154 (2) 221 - 228 2021/09
• TERT promoter mutation status is necessary and sufficient to diagnose IDH-wildtype diffuse astrocytic glioma with molecular features of glioblastoma.

  Kenji Fujimoto; Hideyuki Arita; Kaishi Satomi; Kai Yamasaki; Yuko Matsushita; Taishi Nakamura; Yasuji Miyakita; Toru Umehara; Keiichi Kobayashi; Kaoru Tamura; Shota Tanaka; Fumi Higuchi; Yoshiko Okita; Yonehiro Kanemura; Junya Fukai; Daisuke Sakamoto; Takehiro Uda; Ryunosuke Machida; Aya Kuchiba; Taketoshi Maehara; Motoo Nagane; Ryo Nishikawa; Hiroyoshi Suzuki; Makoto Shibuya; Takashi Komori; Yoshitaka Narita; Koichi Ichimura

  Acta neuropathologica 142 (2) 323 - 338 2021/08
• Fine-Tuning Approach for Segmentation of Gliomas in Brain Magnetic Resonance Images with a Machine Learning Method to Normalize Image Differences among Facilities.

  Satoshi Takahashi; Masamichi Takahashi; Manabu Kinoshita; Mototaka Miyake; Risa Kawaguchi; Naoki Shinojima; Akitake Mukasa; Kuniaki Saito; Motoo Nagane; Ryohei Otani; Fumi Higuchi; Shota Tanaka; Nobuhiro Hata; Kaoru Tamura; Kensuke Tateishi; Ryo Nishikawa; Hideyuki Arita; Masahiro Nonaka; Takehiro Uda; Junya Fukai; Yoshiko Okita; Naohiro Tsuyuguchi; Yonehiro Kanemura; Kazuma Kobayashi; Jun Sese; Koichi Ichimura; Yoshitaka Narita; Ryuji Hamamoto

  Cancers 13 (6) 2021/03
• MPC-11 Comprehensive gene expression analysis of IDH-mutated astrocytomas with 19q-loss

  Ryohei Otani; Akitake Mukasa; Takeo Uzuka; Fumi Higuchi; Hadzki Matsuda; Shota Tanaka; Phyo Kim; Keisuke Ueki

  Neuro-Oncology Advances Oxford University Press (OUP) 2 (Supplement_3) ii12 - ii12 2020/11
• TERT promoter mutation confers favorable prognosis regardless of 1p/19q status in adult diffuse gliomas with IDH1/2 mutations.

  Hideyuki Arita; Yuko Matsushita; Ryunosuke Machida; Kai Yamasaki; Nobuhiro Hata; Makoto Ohno; Shigeru Yamaguchi; Takashi Sasayama; Shota Tanaka; Fumi Higuchi; Toshihiko Iuchi; Kuniaki Saito; Masayuki Kanamori; Ken-Ichiro Matsuda; Yohei Miyake; Kaoru Tamura; Sho Tamai; Taishi Nakamura; Takehiro Uda; Yoshiko Okita; Junya Fukai; Daisuke Sakamoto; Yasuhiko Hattori; Eriel Sandika Pareira; Ryusuke Hatae; Yukitomo Ishi; Yasuji Miyakita; Kazuhiro Tanaka; Shunsaku Takayanagi; Ryohei Otani; Tsukasa Sakaida; Keiichi Kobayashi; Ryuta Saito; Kazuhiko Kurozumi; Tomoko Shofuda; Masahiro Nonaka; Hiroyoshi Suzuki; Makoto Shibuya; Takashi Komori; Hikaru Sasaki; Masahiro Mizoguchi; Haruhiko Kishima; Mitsutoshi Nakada; Yukihiko Sonoda; Teiji Tominaga; Motoo Nagane; Ryo Nishikawa; Yonehiro Kanemura; Aya Kuchiba; Yoshitaka Narita; Koichi Ichimura

  Acta neuropathologica communications 8 (1) 201 - 201 2020/11
• PATH-10. EFFECTS OF 19q-LOSS IN IDH-MUTATED ASTROCYTOMAS ON BETTER PROGNOSIS AND OLIGODENDROGLIOMA-LIKE MORPHOLOGY

  Ryohei Otani; Takeo Uzuka; Fumi Higuchi; Hadzki Matsuda; Shota Tanaka; Akitake Mukasa; Phyo Kim; Keisuke Ueki

  Neuro-Oncology Oxford University Press (OUP) 22 (Supplement_2) ii165 - ii166 1522-8517 2020/11
• PATH-08. EVALUATION OF MISMATCH REPAIR GENE EXPRESSION BY IMMUNOHISTOCHEMISTRY MAY DETECT EARLY PHASE OF MMR DEFICIENCY IN RECURRENT GLIOMAS

  Fumi Higuchi; Hadzki Matsuda; Takeo Uzuka; Phyo Kim; Keisuke Ueki

  Neuro-Oncology Oxford University Press (OUP) 22 (Supplement_2) ii165 - ii165 1522-8517 2020/11
• Poly(ADP-ribose) Glycohydrolase Inhibition Sequesters NAD+ to Potentiate the Metabolic Lethality of Alkylating Chemotherapy in IDH-Mutant Tumor Cells.

  Hiroaki Nagashima; Christine K Lee; Kensuke Tateishi; Fumi Higuchi; Megha Subramanian; Seamus Rafferty; Lisa Melamed; Julie J Miller; Hiroaki Wakimoto; Daniel P Cahill

  Cancer discovery 10 (11) 1672 - 1689 2020/11
• Restoration of Temozolomide Sensitivity by PARP Inhibitors in Mismatch Repair Deficient Glioblastoma is Independent of Base Excision Repair.

  Fumi Higuchi; Hiroaki Nagashima; Jianfang Ning; Mara V A Koerner; Hiroaki Wakimoto; Daniel P Cahill

  Clinical cancer research : an official journal of the American Association for Cancer Research 26 (7) 1690 - 1699 2020/04
• MPC-07 MECHANISMS OF BETTER PROGNOSIS IN IDH-MUTATED ASTROCYTOMA WITH 19Q-LOSS

  Ryohei Otani; Takeo Uzuka; Fumi Higuchi; Hadzki Matsuda; Phyo Kim; Keisuke Ueki

  Neuro-Oncology Advances Oxford University Press (OUP) 1 (Supplement_2) ii23 - ii23 2019/12
• DNA demethylation is associated with malignant progression of lower-grade gliomas.

  Masashi Nomura; Kuniaki Saito; Koki Aihara; Genta Nagae; Shogo Yamamoto; Kenji Tatsuno; Hiroki Ueda; Shiro Fukuda; Takayoshi Umeda; Shota Tanaka; Shunsaku Takayanagi; Ryohei Otani; Takahide Nejo; Taijun Hana; Satoshi Takahashi; Yosuke Kitagawa; Mayu Omata; Fumi Higuchi; Taishi Nakamura; Yoshihiro Muragaki; Yoshitaka Narita; Motoo Nagane; Ryo Nishikawa; Keisuke Ueki; Nobuhito Saito; Hiroyuki Aburatani; Akitake Mukasa

  Scientific reports 9 (1) 1903 - 1903 2019/02
• Brain invasion by chronic lymphocytic leukemia.

  Ryohei Otani; Takeo Uzuka; Hadzki Matsuda; Fumi Higuchi; Phyo Kim; Keisuke Ueki

  Neuropathology : official journal of the Japanese Society of Neuropathology 39 (1) 54 - 57 2019/02
• PLK1 Inhibition Targets Myc-Activated Malignant Glioma Cells Irrespective of Mismatch Repair Deficiency-Mediated Acquired Resistance to Temozolomide.

  Fumi Higuchi; Alexandria L Fink; Juri Kiyokawa; Julie J Miller; Mara V A Koerner; Daniel P Cahill; Hiroaki Wakimoto

  Molecular cancer therapeutics 17 (12) 2551 - 2563 2018/12
• Genotype-targeted local therapy of glioma.

  Ganesh M Shankar; Ameya R Kirtane; Julie J Miller; Hormoz Mazdiyasni; Jaimie Rogner; Tammy Tai; Erik A Williams; Fumi Higuchi; Tareq A Juratli; Kensuke Tateishi; Mara V A Koerner; Shilpa S Tummala; Alexandria L Fink; Tristan Penson; Stephen P Schmidt; Gregory R Wojtkiewicz; Aymen Baig; Joshua M Francis; Mikael L Rinne; Julie M Batten; Tracy T Batchelor; Priscilla K Brastianos; William T Curry Jr; Fred G Barker 2nd; Justin T Jordan; A John Iafrate; Andrew S Chi; Jochen K Lennerz; Matthew Meyerson; Robert Langer; Hiroaki Wakimoto; Giovanni Traverso; Daniel P Cahill

  Proceedings of the National Academy of Sciences of the United States of America 115 (36) E8388-E8394  2018/09
• IDH-mutated astrocytomas with 19q-loss constitute a subgroup that confers better prognosis.

  Ryohei Otani; Takeo Uzuka; Fumi Higuchi; Hadzki Matsuda; Masashi Nomura; Shota Tanaka; Akitake Mukasa; Koichi Ichimura; Phyo Kim; Keisuke Ueki

  Cancer science 109 (7) 2327 - 2335 2018/07
• Histology of hemangioblastoma treated with stereotactic radiosurgery confirms its effectiveness.

  Shohei Nambu; Ryohei Otani; Fumi Higuchi; Takeo Uzuka; Hadzki Matsuda; Phyo Kim; Keisuke Ueki

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 51 43 - 45 2018/05
• Intravascular Lymphoma with an Acute Course of Cerebellar Hemorrhage: A Case Report.

  Takeo Uzuka; Fumi Higuchi; Hadzuki Matsuda; Ryohei Otani; Phyo Kim; Keisuke Ueki

  Neurologia medico-chirurgica 58 (2) 96 - 100 2018/02
• THE ALKYLATING CHEMOTHERAPEUTIC TEMOZOLOMIDE INDUCES METABOLIC STRESS AND POTENTIATES NAD plus DEPLETION-MEDIATED CELL DEATH IN IDH1 MUTANT CANCERS

  Kensuke Tateishi; Julie Miller; Fumi Higuchi; Mara V. A. Koerner; Nina Lelic; William Curry; Tracy Batchelor; Hiroaki Wakimoto; Andrew S. Chi; Daniel Cahill

  NEURO-ONCOLOGY OXFORD UNIV PRESS INC 19 75 - 75 1522-8517 2017/11 [Refereed]
  
• Coordinated Splicing of Regulatory Detained Introns within Oncogenic Transcripts Creates an Exploitable Vulnerability in Malignant Glioma.

  Christian J Braun; Monica Stanciu; Paul L Boutz; Jesse C Patterson; David Calligaris; Fumi Higuchi; Rachit Neupane; Silvia Fenoglio; Daniel P Cahill; Hiroaki Wakimoto; Nathalie Y R Agar; Michael B Yaffe; Phillip A Sharp; Michael T Hemann; Jacqueline A Lees

  Cancer cell 32 (4) 411 - 426 2017/10
• The Alkylating Chemotherapeutic Temozolomide Induces Metabolic Stress in IDH1-Mutant Cancers and Potentiates NAD+ Depletion-Mediated Cytotoxicity.

  Kensuke Tateishi; Fumi Higuchi; Julie J Miller; Mara V A Koerner; Nina Lelic; Ganesh M Shankar; Shota Tanaka; David E Fisher; Tracy T Batchelor; A John Iafrate; Hiroaki Wakimoto; Andrew S Chi; Daniel P Cahill

  Cancer research 77 (15) 4102 - 4115 2017/08
• A nationwide multi-institutional retrospective study to identify prognostic factors and develop a graded prognostic assessment system for patients with brain metastases from uterine corpus and cervical cancer.

  Nakamasa Hayashi; Hideaki Takahashi; Yuzo Hasegawa; Fumi Higuchi; Masamichi Takahashi; Keishi Makino; Masatoshi Takagaki; Jiro Akimoto; Takeshi Okuda; Yoshiko Okita; Koichi Mitsuya; Yasuyuki Hirashima; Yoshitaka Narita; Yoko Nakasu

  BMC cancer 17 (1) 397 - 397 2017/06
• CHEMOTHERAPY-INDUCED METABOLIC STRESS IN IDH1 MUTANT GLIOMAS

  Tateishi Kensuke; Wakimoto Hiroaki; Higuchi Fumi; Miller Julie; Koerner Mara V. A; Lelic Nina; Shankar Ganesh; Tanaka Shota; Curry William T; Fisher David E; Batchelor Tracy T; Iafrate A. John; Chi Andrew S; Cahill Daniel P

  NEURO-ONCOLOGY 18 (11) 1559 - 1568 1523-5866 2016/11 [Refereed]
  
• A combination of TERT promoter mutation and MGMT methylation status predicts clinically relevant subgroups of newly diagnosed glioblastomas.

  Hideyuki Arita; Kai Yamasaki; Yuko Matsushita; Taishi Nakamura; Asanao Shimokawa; Hirokazu Takami; Shota Tanaka; Akitake Mukasa; Mitsuaki Shirahata; Saki Shimizu; Kaori Suzuki; Kuniaki Saito; Keiichi Kobayashi; Fumi Higuchi; Takeo Uzuka; Ryohei Otani; Kaoru Tamura; Kazutaka Sumita; Makoto Ohno; Yasuji Miyakita; Naoki Kagawa; Naoya Hashimoto; Ryusuke Hatae; Koji Yoshimoto; Naoki Shinojima; Hideo Nakamura; Yonehiro Kanemura; Yoshiko Okita; Manabu Kinoshita; Kenichi Ishibashi; Tomoko Shofuda; Yoshinori Kodama; Kanji Mori; Yusuke Tomogane; Junya Fukai; Koji Fujita; Yuzo Terakawa; Naohiro Tsuyuguchi; Shusuke Moriuchi; Masahiro Nonaka; Hiroyoshi Suzuki; Makoto Shibuya; Taketoshi Maehara; Nobuhito Saito; Motoo Nagane; Nobutaka Kawahara; Keisuke Ueki; Toshiki Yoshimine; Etsuo Miyaoka; Ryo Nishikawa; Takashi Komori; Yoshitaka Narita; Koichi Ichimura

  Acta neuropathologica communications 4 (1) 79 - 79 2016/08
• A Multicenter Phase I/II Study of the BCNU Implant (Gliadel® Wafer) for Japanese Patients with Malignant Gliomas

  Tomokazu AOKI; Ryo NISHIKAWA; Kazuhiko SUGIYAMA; Naosuke NONOGUCHI; Noriyuki KAWABATA; Kazuhiko MISHIMA; Jun-ichi ADACHI; Kaoru KURISU; Fumiyuki YAMASAKI; Teiji TOMINAGA; Toshihiro KUMABE; Keisuke UEKI; Fumi HIGUCHI; Tetsuya YAMAMOTO; Eiichi ISHIKAWA; Hideo TAKESHIMA; Shinji YAMASHITA; Kazunori ARITA; Hirofumi HIRANO; Shinobu YAMADA; Masao MATSUTANI

  Neurologia medico-chirurgica Japan Neurosurgical Society 54 (4) 290 - 301 0470-8105 2014/04 [Refereed]
  
• A multicenter phase I/II study of the BCNU implant (Gliadel(®) Wafer) for Japanese patients with malignant gliomas.

  Tomokazu Aoki; Ryo Nishikawa; Kazuhiko Sugiyama; Naosuke Nonoguchi; Noriyuki Kawabata; Kazuhiko Mishima; Jun-ichi Adachi; Kaoru Kurisu; Fumiyuki Yamasaki; Teiji Tominaga; Toshihiro Kumabe; Keisuke Ueki; Fumi Higuchi; Tetsuya Yamamoto; Eiichi Ishikawa; Hideo Takeshima; Shinji Yamashita; Kazunori Arita; Hirofumi Hirano; Shinobu Yamada; Masao Matsutani

  Neurologia medico-chirurgica 54 (4) 290 - 301 2014
• Metastasis to the choroid plexus from thyroid cancer: case report.

  Yosuke Kitagawa; Fumi Higuchi; Yoshihiro Abe; Hadzuki Matsuda; Phyo Kim; Keisuke Ueki

  Neurologia medico-chirurgica 53 (11) 832 - 6 2013
• Effectiveness of a 1-day aspiration plus Gamma Knife surgery procedure for metastatic brain tumor with a cystic component.

  Fumi Higuchi; Shunsuke Kawamoto; Yoshihiro Abe; Phyo Kim; Keisuke Ueki

  Journal of neurosurgery 117 Suppl 17 - 22 2012/12
• Metastatic brain sarcoma with gliomatous component.

  Fumi Higuchi; Hadzuki Matsuda; Yoshifumi Okada; Phyo Kim; Keisuke Ueki

  Brain tumor pathology 28 (4) 365 - 9 2011/10

MISC

• 脳実質内腫瘍として中枢神経転移した多発性骨髄腫転移性脳腫瘍の一例

  中村 祐基; 樋口 芙未; 白崎 良輔; 松本 謙介; 石田 毅; 斉藤 光次; 宇於崎 宏; 笹島 ゆう子; 庄島 正明; 辛 正廣  Brain Tumor Pathology  40-  (Suppl.)  147  -147  2023/05
• 悪性脳腫瘍のジェネテイクス

  樋口 芙未; 植木 敬介  糖尿病・内分泌代謝科  55-  (1)  114  -118  2022/07
• 術前画像診断に苦慮したDiffuse hemispheric glioma、H3 G34-mutantの一例 WHO第5版にどう対応するか

  大本 裕次郎; 樋口 芙未; 木倉 亮太; 後藤 芳明; 沼倉 里枝; 庄島 正明; 斉藤 光次; 笹島 ゆう子; 横尾 英明; 辛 正廣  Brain Tumor Pathology  39-  (Suppl.)  117  -117  2022/05
• MOLECULAR PROFILING OF SPINAL CORD EPENDYMOMA

  Erika Yamazawa; Shota Tanaka; Genta Nagae; Takayoshi Umeda; Taijun Hana; Phyo Kim; Fumi Higuchi; Toshihiro Takami; Yuta Nakanishi; Keisuke Takai; Takashi Komori; Hirokazu Takami; Masashi Nomura; Akitake Mukasa; Shunsaku Takayanagi; Kazuhiko Ishii; Hideaki Imai; Reiko Matsuura; Tsukasa Koike; Yoshihiro Kushihara; Shohei Nambu; Kazuha Kugasawa; Hiroyuki Aburatani; Nobuhito Saito  NEURO-ONCOLOGY  23-  1  -1  2021/11
• 成人脊髄H3K27M mutant gliomaの5例

  糸岐 一茂; 松田 葉月; 黒川 龍; 新郷 哲郎; 田中 將太; 山澤 恵梨香; 宇塚 岳夫; 樋口 芙未; 植木 敬介; 金 彪  Brain Tumor Pathology  38-  (Suppl.)  079  -079  2021/05
• 初発時にTP53変異を認め再発時にMSH6変異を伴いhypermutatorとなった退形成性乏突起膠腫の一例

  樋口 芙未; 松田 葉月; 岩田 佳代子; 宇塚 岳夫; 植木 敬介  Brain Tumor Pathology  38-  (Suppl.)  107  -107  2021/05
• 成人脊髄diffuse midline gliomaはしばしばsubclonalなH3K27M変異を有する 5症例の検討

  松田 葉月; 糸岐 一茂; 黒川 龍; 新郷 哲郎; 田中 將太; 山澤 恵梨香; 宇塚 岳夫; 樋口 芙未; 植木 敬介; 金 彪  Brain Tumor Pathology  38-  (Suppl.)  111  -111  2021/05
• PREDICTORS OF SENSITIVITY TO COMBINED TEMOZOLOMIDE AND PARP INHIBITOR IN GLIOMA

  Hiroaki Nagashima; Fumi Higuchi; Christine Lee; Seamus Rafferty; Julie Miller; Hiroaki Wakimoto; Daniel Cahill  NEURO-ONCOLOGY  21-  72  -72  2019/11
• 術前塞栓術を施行した孤立性線維性腫瘍/血管周皮腫におけるSTAT3免疫染色の染色性保持に関する検討

  松田 葉月; 宇塚 岳夫; 樋口 芙未; 矢島 寛久; 石川 美保子; 金 彪; 植木 敬介  Brain Tumor Pathology  35-  (Suppl.)  184  -184  2018/09
• PLK1 INHIBITOR TARGETS MISMATCH REPAIR DEFICIENT TEMOZOLOMIDE RESISTANT GLIOMA

  Fumi Higuchi; Daniel Cahill; Hiroaki Wakimoto  NEURO-ONCOLOGY  19-  86  -86  2017/11
• IDH-MUTATED, 19q DELETED, TP53 MUTATED ANAPLASTIC GLIOMAS CONSTITUTE A SUBGROUP THAT LOOK LIKE AND BEHAVE LIKE ANAPLASTIC OLIGODENDROGLIOMAS

  Ryohei Otani; Takeo Uzuka; Fumi Higuchi; Hazuki Matsuda; Shota Tanaka; Akitake Mukasa; Kohichi Ichimura; Phyo Kim; Keisuke Ueki  NEURO-ONCOLOGY  19-  175  -175  2017/11
• PARP INHIBITORS RESTORE TEMOZOLOMIDE SENSITIVITY IN MSH6-DEFICIENT TEMOZOLOMIDE-RESISTANT GLIOMA MODELS

  Fumi Higuchi; Hiroaki Wakimoto; Daniel Cahill  NEURO-ONCOLOGY  19-  67  -67  2017/11
• 子宮 婦人科がん治療の新展開 子宮がん脳転移の患者における生存期間予測と治療指針 新しいGPAの開発と検証

  林 央周; 高橋 英明; 長谷川 祐三; 樋口 芙未; 高橋 雅道; 牧野 敬史; 高垣 匡寿; 秋元 治朗; 奥田 武司; 沖田 典子; 三矢 幸一; 平嶋 泰之; 成田 善孝; 中洲 庸子  日本癌治療学会学術集会抄録集  54回-  WS61  -1  2016/10
• 子宮 子宮体がん治療の新たな工夫 子宮癌脳転移の予後予測因子に関する多施設共同研究

  林 央周; 高橋 英明; 長谷川 祐三; 樋口 芙未; 高橋 雅道; 牧野 敬史; 高垣 匡寿; 秋元 治朗; 奥田 武司; 沖田 典子; 三矢 幸一; 平嶋 泰之; 成田 善孝; 中洲 庸子  日本癌治療学会誌  50-  (3)  1130  -1130  2015/09
• グリオーマの病理と分子解析 1p/19q co-deletedグリオーマの再発例の組織学的、分子遺伝学的検討

  植木 敬介; 相原 功輝; 樋口 芙未; 宇塚 岳夫; 松田 葉月; 油谷 浩幸; 金 彪  Brain Tumor Pathology  32-  (Suppl.)  065  -065  2015/05
• HISTOLOGICAL EXAMINATION OF ENHANCING LESION ADJACENT TO THE IMPLANTED BCNU-WAFERS SUGGESTS VASCULAR DAMAGE AS THE MAJOR UNDERLYING MECHANISM

  Keisuke Ueki; Hadzki Matsuda; Fumi Higuchi; Takeo Udzuka; Phyo Kim  NEURO-ONCOLOGY  16-  2014/11
• GENETIC AND HISTOLOGICAL STABILITY OF OLIGODENDROGLIAL TUMORS WITH 1P/19Q CO-DELETION EVEN AFTER CHEMOTHERAPY AND OR RADIATION THERAPY

  Keisuke Ueki; Koki Aihara; Akitake Mukasa; Fumi Higuchi; Hazki Matsuda; Phyo Kim  NEURO-ONCOLOGY  16-  2014/07
• OLIGOASTROCYTOMA CAN BE DEVIDED TO THREE SUBGROUPS BY MOLECULAR MARKERS AND HISTOLOGICAL FEATURES

  Fumi Higuchi; Hadzuki Matsuda; Kayoko Iwata; Keisuke Ueki; Phyo Kim  NEURO-ONCOLOGY  15-  158  -158  2013/11

Research Grants & Projects

• ミスマッチ修復欠損神経膠腫細胞に対するTMZ抵抗性を克服する新治療の開発

  日本学術振興会：科学研究費助成事業

  Date (from‐to) : 2020/04 -2023/03 

  Author : 樋口 芙未
• PARP阻害剤による神経膠腫細胞に対するTMZ抵抗性克服に関する研究

  獨協医学医学教育研究財団賞

  Date (from‐to) : 2020/04 -2021/03