Takahashi Senji

Researcher Information

Affiliation

Department of Integrated Science and Engineering,Environment and Biotechnology Course Professor
Graduate School of Science and Engineering Professor
Division of Integrated Science and Engineering Professor

URL

https://jglobal.jst.go.jp/detail?JGLOBAL_ID=202001005319568032

Research funding number

• 00236291

J-Global ID

• 202001005319568032

Research Interests

• bioactive compounds   natural products chemistry   

Research Areas

• Life sciences / Bioorganic chemistry

Academic & Professional Experience

• 2020/04 - Today  Teikyo UniversityFaculty of Science and Engineering Department of Biosciences
• 2010/04 - 2020/03  Teikyo UniversityFaculty of Science and Engineering Department of Biosciences
• 2005/04 - 2010/03  Teikyo UniversityFaculty of Science and Engineering Department of Biosciences
• 1991/04 - 2005/03  Teikyo UniversityFaculty of Science and Engineering Department of Biosciences

Education

• 1985/04 - 1987/03  Tokyo University of Science  Graduate School of Science
• 1981/04 - 1985/03  Tokyo University of Science

Research Activity Information

Published Papers

• A new metabolite, mannogeranylnerol, specifically produced at body temperature by Schizophyllum commune, a causative fungus of human mycosis.

  Shing Yiu Tam; Kenichi Uchida; Hirofumi Enomoto; Senji Takahashi; Koichi Makimura; Shohei Sakuda

  The Journal of antibiotics 75 (4) 243 - 246 2022/04 [Refereed]
  
• Light dependent accumulation of beta-carotene enhances photo-acclimation of Euglena gracilis

  Yuri Tanno; Shota Kato; Senji Takahashi; Shun Tamaki; Shinichi Takaichi; Yutaka Kodama; Kintake Sonoike; Tomoko Shinomura

  JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY ELSEVIER SCIENCE SA 209 1011-1344 2020/08 [Refereed]
  
• Distribution of Flavan-3-ol Species in Ripe Strawberry Fruit Revealed by Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry Imaging

  Hirofumi Enomoto; Senji Takahashi; Shiro Takeda; Hajime Hatta

  Molecules MDPI AG 25 (1) 103 - 103 2020 [Refereed]
  
• Identification and functional analysis of the geranylgeranyl pyrophosphate synthase gene (crtE) and phytoene synthase gene (crtB) for carotenoid biosynthesis in Euglena gracilis

  Shota Kato; Shinichi Takaichi; Takahiro Ishikawa; Masashi Asahina; Senji Takahashi; Tomoko Shinomura

  BMC Plant Biology Springer Science and Business Media LLC 16 (1) 1471-2229 2016/12 [Refereed]
  
• Changes in polyamine levels in Xenopus early embryogenesis.

  K. Shiokawa; T. Mishina; H. Yoshida; J. Takai; K. Tsuboshima; T. Soutome; T. Terui; H. Abe; S. Sakurai; S. Takahashi; K. Tashiro; K. Igarashi

  Trends Develop. Biol. 7 25 - 31 2013 [Refereed]
  
• Polyamines added to the culture medium of Xenopus fertilized eggs induce massive cell dissociation at the blastula stage by interfering with Ca2+-dependent cell adhesion.

  K. Shiokawa; T. Kondo; S. Takahashi; K. Igarashi

  Amino Acids. SPRINGER WIEN 45 (3) 571 - 572 0939-4451 2013 [Refereed]
  
• Gene Expression in Pre-MBT Embryos and Activation of Maternally-Inherited Program of Apoptosis to be Executed at around MBT as a Fail-Safe Mechanism inXenopusEarly Embryogenesis

  Koichiro Shiokawa; Mai Aso; Takeshi Kondo; Hiroaki Uchiyama; Shinsaku Kuroyanagi; Jun-Ichi Takai; Senji Takahashi Masayuki Kajitani; Chikara Kaito; Kazuhisa Sekimizu; Eiji Takayama; Kazuei Igarashi; Hiroshi Hara

  Gene Regulation and Systems Biology SAGE Publications 2 213 - 231 1177-6250 2008/01 [Refereed]
  
• Byelyankacin: A Novel Melanogenesis Inhibitor Produced by Enterobacter sp. B20

  Senji Takahashi; Hiroki Iwai; Kunio Kosaka; Toshitsugu Miyazaki; Yuko Osanai; Nakako Arao; Kouichi Tanaka; Koji Nagai; Akira Nakagawa

  The Journal of Antibiotics Springer Science and Business Media LLC 60 (11) 717 - 720 0021-8820 2007 [Refereed]
  
• Biosynthesis of Quinolactacin A, a TNF Production Inhibitor

  Tatsuya Sasaki; Senji Takahashi; Kenichi Uchida; Shinji Funayama; Masatsune Kainosho; Akira Nakagawa

  The Journal of Antibiotics Springer Science and Business Media LLC 59 (7) 418 - 427 0021-8820 2006 [Refereed]
  
• Screening of Actinomycetes with antinematodal properties.

  KAZUYOSHI CHUBACHI; MAKOTO FURUKAWA; SHIGEAKI FUKUDA; SENJI TAKAHASHI; TADASHI YANAGISAWA; HIDEO ITAGAWA; TERUO SHIMIZU; AKIRA NAKAGAWA

  Biocontrol Science The Society for Antibacterial and Antifungal Agents, Japan 7 (1) 49 - 54 1342-4815 2002 [Refereed]
  
• Adxanthromycins A and B, New Inhibitors of ICAM-1/LFA-1 Mediated Cell Adhesion Molecule from Streptomyces sp. NA-148. I. Taxonomy, Production, Isolation and Biological Activities.

  TAKAYUKI NAKANO; TSUKASA KOIWA; SENJI TAKAHASHI; AKIRA NAKAGAWA

  The Journal of Antibiotics Japan Antibiotics Research Association 53 (1) 12 - 18 0021-8820 2000 [Refereed]
  
• Adxanthromycins A and B, New Inhibitors of ICAM-1/LFA-1 Mediated Cell Adhesion Molecule from Streptomyces sp. NA-148. II. Physico-chemical Properties and Structure Elucidation.

  SENJI TAKAHASHI; TAKAYUKI NAKANO; TSUKASA KOIWA; TOSHIRO NOSHITA; SHINJI FUNAYAMA; HIROYUKI KOSHINO; AKIRA NAKAGAWA

  The Journal of Antibiotics Japan Antibiotics Research Association 53 (2) 163 - 170 0021-8820 2000 [Refereed]
  
• Quinolactacins A, B and C. Novel Quinolone Compounds from Penicillium sp. EPF-6. I. Taxonomy, Production, Isolation and Biological Properties.

  NORIHIRO KAKINUMA; HIROKI IWAI; SENJI TAKAHASHI; KUNIKATSU HAMANO; TADASHI YANAGISAWA; KOJI NAGAI; KOICHI TANAKA; KENICHI SUZUKI; FUMIKO KIRIKAE; TERUO KIRIKAE; AKIRA NAKAGAWA

  The Journal of Antibiotics Japan Antibiotics Research Association 53 (11) 1247 - 1251 0021-8820 2000 [Refereed]
  
• Quinolactacins A, B and C. Novel Quinolone Compounds from Penicillium sp. EPF-6. II. Physico-chemical Properties and Structure Elucidation.

  SENJI TAKAHASHI; NORIHIRO KAKINUMA; HIROKI IWAI; TADASHI YANAGISAWA; KOJI NAGAI; KENICHI SUZUKI; TATSUHIRO TOKUNAGA; AKIRA NAKAGAWA

  The Journal of Antibiotics Japan Antibiotics Research Association 53 (11) 1252 - 1256 0021-8820 2000 [Refereed]
  
• Inhibitory Effect of Antimicrobial Agents on Alginate Production in Pseudomonas aeruginosa.

  TAKAYUKI HOSOYAMA; TAKEHIRO YUGE; SENJI TAKAHASHI; TOMOO SUZUKI; TOYOJI OKUBO; SHIZUKO IYOBE; AKIRA NAKAGAWA

  The Journal of Antibiotics Japan Antibiotics Research Association 52 (1) 65 - 67 0021-8820 1999 [Refereed]
  
• Adxanthromycin: A New Inhibitor of ICAM-1/LFA-1 Mediated Cell Adhesion from Streptomyces sp. NA-148.

  TSUKASA KOIWA; TAKAYUKI NAKANO; SENJI TAKAHASHI; HIROYUKI KOSHINO; MIKA YAMAZAKI; TOHRU TAKASHI; AKIRA NAKAGAWA

  The Journal of Antibiotics Japan Antibiotics Research Association 52 (2) 198 - 200 0021-8820 1999 [Refereed]
  
• Control of Root-knot Nematodes by Streptomyces: Screening of Root-knot Nematode-controlling Actinomycetes and Evaluation of Their Usefulness in a Pot Test

  Kazuyoshi CHUBACHI; Makoto FURUKAWA; Shigeaki FUKUDA; Senji TAKAHASHI; Shoji MATSUMURA; Hideo ITAGAWA; Teruo SHIMIZU; Akira NAKAGAWA

  Nematological Research (Japanese Journal of Nematology) The Japanese Nematological Society 29 (2) 42 - 45 0919-6765 1999 [Refereed]
  
• Pyridovericin and Pyridomacrolidin: Novel Metabolites from Entomopathogenic Fungi, Beauveria bassiana.

  SENJI TAKAHASHI; NORIHIRO KAKINUMA; KENICHI UCHIDA; RYUJU HASHIMOTO; TADASHI YANAGISAWA; AKIRA NAKAGAWA

  The Journal of Antibiotics Japan Antibiotics Research Association 51 (6) 596 - 598 0021-8820 1998 [Refereed]
  
• The Structures of Pyridovericin and Pyridomacrolidin, New Metabolites from the Entomopathogenic Fungus, Beauveria bassiana.

  SENJI TAKAHASHI; KENICHI UCHIDA; NORIHIRO KAKINUMA; RYUJU HASHIMOTO; TADASHI YANAGISAWA; AKIRA NAKAGAWA

  The Journal of Antibiotics Japan Antibiotics Research Association 51 (11) 1051 - 1054 0021-8820 1998 [Refereed]
  
• A Search for Pseudomonas Alginate Biosynthesis Inhibitors from Microbial Metabolites

  AKIRA NAKAGAWA; TAKAYUKI HOSOYAMA; KAZUYOSHI CHUBACHI; SENJI TAKAHASHI; TOYOJI OHKUBO; SHIZUKO IYOBE

  The Journal of Antibiotics Japan Antibiotics Research Association 50 (3) 286 - 288 0021-8820 1997 [Refereed]
  
• Melanoxazal, New Melanin Biosynthesis Inhibitor Discovered by Using the Larval Haemolymph of the Silkworm, Bombyx mori. Production, Isolation, Structural Elucidation, and Biological Properties.

  SENJI TAKAHASHI; RYUJU HASHIMOTO; KUNIKATSU HAMANO; TOMOO SUZUKI; AKIRA NAKAGAWA

  The Journal of Antibiotics Japan Antibiotics Research Association 49 (6) 513 - 518 0021-8820 1996 [Refereed]
  
• Biosynthesis of Lactacystin.

  SENJI TAKAHASHI; KENICHI UCHIDA; AKIRA NAKAGAWA; YOKO MIYAKE; MASATSUNE KAINOSHO; KEIICHI MATSUZAKI; SATOSHI OMURA

  The Journal of Antibiotics Japan Antibiotics Research Association 48 (9) 1015 - 1020 0021-8820 1995 [Refereed]
  
• A New Melanin Biosynthesis Inhibitor, Melanoxadin from Fungal Metabolite by Using the Larval Haemolymph of the Silkworm, Bombyx mori.

  RYUJU HASHIMOTO; SENJI TAKAHASHI; KUNIKATSU HAMANO; AKIRA NAKAGAWA

  The Journal of Antibiotics Japan Antibiotics Research Association 48 (9) 1052 - 1054 0021-8820 1995 [Refereed]
  
• Biosynthesis of lactacystin. Origin of the carbons and stereospecific NMR assignment of the two diastereotopic methyl groups

  Akira Nakagawa; Senji Takahashi; Kenichi Uchida; Keiichi Matsuzaki; Satoshi Ōmura; Asao Nakamura; Noboru Kurihara; Tsuyoshi Nakamatsu; Yoko Miyake; Kanako Take; Masatsune Kainosho

  Tetrahedron Letters Elsevier BV 35 (28) 5009 - 5012 0040-4039 1994/07 [Refereed]
  
• New Method for Screening the Melanin Biosynthesis Inhibitor by Using the Larval Haemolymph of the Silkworm,Bombyx mori, and the Inhibitory Activity of Trichoviridin

  Ryuju Hashimoto; Senji Takahashi; Kunikatsu Hamano; Tadasu Mori; Akira Nakagawa

  Bioscience, Biotechnology, and Biochemistry Informa UK Limited 58 (9) 1725 - 1726 0916-8451 1994/01 [Refereed]
  
• Samarium (III) iodide promoted addition of diketene to aldehydes : A facile synthesis of δ-hydroxy-β-oxocarboxylates.

  Koji Abe; Senji Takahashi; Nobuo Mori

  Chemistry Express 6 (3) 193 - 196 1991/03 [Refereed]
  
• Radical coupling of β-bromostyrene with carbonyl compounds promoted by samarium (II) di-iodide.

  Koji Abe; Katsuhiko Uehara; Senji Takahashi; Nobuo Mori

  Chemistry Express 6 (3) 189 - 192 1991/03 [Refereed]
  
• Reductive cross-coupling of pyruvates with carbonyl compounds mediated by SmI2 : A facile synthesis of α,β-dihydroxycarboxylates.

  Koji Abe; Senji Takahashi; Nobuo Mori

  Chemistry Express 6 (1) 53 - 56 1991/01 [Refereed]
  
• Samarium(II) diiodide mediated coupling of bis(bromomethyl)arenes. Facile synthesis of [2n]cyclophanes without using high-dilution techniques

  Senji Takahashi; Nobuo Mori

  Journal of the Chemical Society, Perkin Transactions 1 (8) 2029 - 2032 1472-7781 1991 [Refereed]
  
• Novel transannular reactions in the acid hydrolysis of diazotized syn- and anti-4-amino[2.2] (1,4)naphthalenoparacyclophanes

  Yoshihiro Takada; Kazuhiko Tsuchiya; Senji Takahashi; Nobuo Mori

  Journal of the Chemical Society, Perkin Transactions 2 (12) 2141 - 2145 1472-779X 1990 [Refereed]
  
• A Simple Synthetic Method of [2.2]Cyclophanes by Lanthanoid-Mediated Coupling of Bis(bromomethyl)benzenes

  Senji Takahashi; Nobuo Mori

  Chemistry Letters 18 (1) 13 - 14 1989/01 [Refereed]
  

Research Grants & Projects

• Finding of new bioactive compounds from microorganisms, on the base of biosyunthetic studies on microbial secondary metabolites.

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 1992 -1993 

  Author : NAKAGAWA Akira; TAKAHASHI Senji